BOC-N-ME-AMINOBENZOIC ACID

BOC-N-ME-AMINOBENZOIC ACID - Names and Identifiers

Name	Boc-N-Me-Abz-OH
Synonyms	Boc-MANT BOC-MEABZ-OH BOC-N-ME-ABZ-OH Boc-N-Me-Abz-OH BOC-N-ME-2-ABZ-OH BOC-N-ME-AMINOBENZOIC ACID ANTHRANILIC ACID, N-BOC-N-METHYL BOC-N-METHYL-2-AMINOBENZOIC ACID N-T-BUTOXYCARBONYL-N-METHYL-2-AMINOBENZOIC ACID 2-(tert-Butoxycarbonyl-methyl-amino)-benzoic acid 2-[(tert-butoxycarbonyl)(methyl)amino]benzoic acid
CAS	141871-02-5
InChI	InChI=1/C13H17NO4/c1-13(2,3)18-12(17)14(4)10-8-6-5-7-9(10)11(15)16/h5-8H,1-4H3,(H,15,16)

BOC-N-ME-AMINOBENZOIC ACID - Physico-chemical Properties

Molecular Formula	C13H17NO4
Molar Mass	251.28
Density	1.199±0.06 g/cm3(Predicted)
Boling Point	367.0±25.0 °C(Predicted)
Flash Point	175.8°C
Vapor Presure	4.94E-06mmHg at 25°C
Appearance	Yellow powder
pKa	3.68±0.36(Predicted)
Storage Condition	2-8°C
Refractive Index	1.56
MDL	MFCD00237567

BOC-N-ME-AMINOBENZOIC ACID - Introduction

2-tert-butoxycarbonylaminomethyl-benzoic acid, chemical formula C14H19NO4, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: 2-tert-butoxycarbonylaminomethyl-benzoic acid is commonly white to yellowish crystalline powder.
2. Solubility: It is soluble in most organic solvents, such as methanol, ethanol, dichloromethane, etc.
3. Melting point: about 60-70°C.
4. Stability: relatively stable at room temperature.

Use:
1. pharmaceutical field: 2-tert-butoxycarbonylaminomethyl-benzoic acid is a drug intermediate, commonly used in the synthesis of biologically active molecules. It is widely used in the synthesis of anti-inflammatory, antibacterial, anti-tumor drugs.
2. Other fields: 2-tert-butoxycarbonylaminomethyl-benzoic acid can also be used in the production of functional coatings, dyes and other chemical products.

Preparation Method:
The preparation of 2-tert-butoxycarbonylaminomethyl-benzoic acid can be carried out by the following steps:
1. benzoyl chloride is reacted with methanol to obtain benzoyl methyl ether.
2. reacting benzoyl methyl ether with tert-butylamine to obtain N-tert-butoxybenzamide.
3. Finally, N-tert-butoxybenzamide is subjected to hydrazide to generate 2-tert-butoxycarbonylaminomethyl-benzoic acid.

Safety Information:
1. 2-tert-butoxycarbonylaminomethyl-benzoic acid may have irritating effect on eyes, skin and mucous membrane, and should be washed with plenty of water in time after contact.
2. use should wear appropriate protective equipment, such as protective glasses, gloves and protective clothing.
3. Avoid inhaling dust or steam and ensure that the operating site is well ventilated.
4. in the use and storage process, please follow the relevant safety procedures and protective measures.
5. such as eating or other accidents, please timely medical treatment and bring packaging for processing.

Last Update：2024-04-09 21:00:56